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A Review on Anti-Malarial Activities of Selected Plant Species from the Rutaceae Family

Lawal IO, Olagoke TH

Advancement in phytochemical studies in medicinal plants has really helped in the production of helpful medicinal drugs. This review is aimed at investigating the anti-malarial properties of herbal plant extract so as to complement the effort to find a better and more efficient way of eradicating malaria from African countries. Clausena anisata, Zanthoxylum chalybeum and Toddalia asiatica were reviewed. The extract from C. anisata was found to possess antimalarial activities which are due to some secondary metabolite available in the plants such as alkaloid, flavonoids, monoterpenes and triterpenoids. This review shows that organic solvents of the leaf extracts of selected species contains secondary metabolite compounds with antiplasmodial activity as well as the root bark which has also been reported to have significant effect on P. falciparum. This review shed more light on the significance of Rutaceae family and its antimalarial properties.