Hao Yan, Ruzhan Yao, Mingdong Yu, Rongsheng Dou, Yu Zhang, Huaibin Wang, Yulin Shi, Weiqiang Liu*
Background: Absorbable fluid gelatin is a novel collagen hemostatic agent that has been validated in multiple surgical procedures. However, the effectiveness of using this hemostatic agent during Percutaneous Endoscopic Unilateral Laminectomy for Bilateral Decompression (PE-ULBD) remains controversial. Our research aims to conduct a prospective randomized controlled trial to investigate the effectiveness and safety of this hemostatic material in patients undergoing PE-ULBD for Lumbar Spinal Stenosis (LSS).
Materials and methods: From October, 2023 to May, 2024 a total of 90 patients with LSS who underwent PE-ULBD, were enrolled in this study. The 90 patients were randomly divided into two groups: Group A (45 cases, using fluid gelatin) and group B (45 cases, not using fluid gelatin). Primary outcomes included perioperative blood loss and the success rate of achieving hemostasis within 3 min. Secondary outcomes encompassed surgical time, intraoperative blood loss, length of stay and complications.
Conclusion: When patients with LSS undergo PE-ULBD, the prophylactic use of fluid gelatin can reduce postoperative bleeding without any observed additional complications. Therefore, the prophylactic use of fluid gelatin in PE-ULBD is an effective and safe strategy.
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