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Glycyrrhiza glabra: A Potent Herb from Traditional to Modern Medicine

Md Nasar Mallick

Introduction: Glycyrrhiza glabra, an ayurvedic herb has had much medical importance since ancient times. It has anti-inflammatory action, anti-diabetic action, anti-viral, anti-cancer, expectorant as well as antitussive characteristics, antimicrobial, anti-ulcer, and hepatoprotective action. The primary medicinal components are the root, leaves, and rhizomes. Ayurvedic plants have possessed varieties of medicine values from ancient times, and Glycyrrhiza glabra has been chosen for evaluation based on its chemical components and pharmacological activity.

Methods: Methodology used to define the anti-inflammatory action, anti-diabetic action, anti-viral, anti-cancer, expectorant, antitussive characteristics, antimicrobial, anti-ulcer, and hepatoprotective action with a focus on Glycerrhiza glabra potential activity in various modern pathophysiological conditions.

Results: General pathophysiological aspects to target with Glycerrhiza glabra.

Discussion: The primary goal of the review is to demonstrate the various chemical components and pharmacological activity of Glycyrrhiza glabra with targeting various anti-inflammatory pathways like JACK-STAT, MAPK, COX2, and TXA-2 as well as anti-viral, anti-diabetic, expectorant and antitussive, anti-cancer, antimicrobial, anti-ulcer and hepatoprotective.