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Endocrine Disruptors, Nutraceuticals and their Simultaneous Effects in Hormone-Sensitive Tissues: A Review

Alzbeta Bujnakova Mlynarcikova and Sona Scsukova

The increase in hormone-sensitive types of cancers as well as in fertility problems has been linked to population burden with environmental endocrine disruptors (EDs). On the other hand, antioxidant or chemo preventive properties of various phytochemicals are known, resulting in an increased interest in intake of supplements containing various vitamins or herbal extracts. Thus, organism is exposed simultaneously to xenobiotics of various origins; however, until now there is only limited data and inconsistent results on the combined effects of EDs and nutraceuticals. The aim of this minireview is to provide a brief summary on the issue of EDs, nutraceuticals, and to discuss some of the data available on their simultaneous effects obtained through experimental research, with the focus on the effects on reproductive parameters and hormone-related types of cancer