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A Short Communication on Pharmacokinetic Parameters of Vancomycin used in Severe Infections in Children

Bo Zhou, Yan Zhou, Yue-Qiang Fu, Jing Li, Chengjun Liu*, Wenhui Lv

Infectious diseases are one of the main diseases in children, and Gram-Positive Bacteria (GPB) infection is an important part of them. For the treatment of GPB, vancomycin is our "last line of defense". By monitoring and calculating the pharmacokinetic parameters of vancomycin and formulating individualized vancomycin administration regimen, it plays a very important role in improving the outcome of GPB infection in children. The current article reviews the application of vancomycin pharmacokinetic parameters in severe infections in children.