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Empirical Antibiotic Therapy and Emerging Drug Resistance

Chandrasekaran Venkates, Thiyagarajan Suganya, Dhandapani Gunasekaran, Palanisamy Soundararajan, and VN Mahalakshmi

Antibiotics in inappropriate doses and for inappropriate pathogens without microbiological evidence and drug susceptibility testing are a rampant practice in medicine of late. Two children with different infections with resistance to first line conventional antibiotics with emphasis on inappropriate hospitalization practices and empirical therapy as probable causes of drug resistance and ways of addressing this complex issue is discussed with relevant review of literature.