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Synthesis and Screening of Biological Activities of Some Important Pyrazoline Derivatives

N. M. Chavhan, P. V. Badadhe2, S. N. Shelke

An innovative progression of synthetic pyrazolines derivatives (4a-f) have been synthesized via usual process producing high-quality yield in ethanol through cyclization reaction of chalcones (3a-f), by means of hydrazine hydrate and few drops of glacial acetic acid. Those prepared compounds had been screened for their antimicrobial activities which give an idea about reasonable to good activity against a variety of strains of bacteria and fungi employed. These prepared compounds had been established with IR, 1HNMR and mass spectral statistics.