Абстрактный

Re-Evaluating Antidiabetic Effect of Pioglitazone in Alloxan Induced Diabetic Animal Model

Saurabh Srivastava, Shalini Gupta, Devendra Kumar, and Rakesh Kumar Dixit

The study includes the pharmacological screening on Pioglitazone, which is an effective and frequently prescribed treatment for type 2 diabetes. An in-vivo study included three animal models with six mice in each, one was control or untreated and other two groups were alloxan and one group drug treated to compare the pharmacological response of pioglitazone against diabetic. Alloxan was used to induce diabetes in animals. Alloxan, a β-cytotoxin, chemically called mesoxalylurea, mesoxalylcarbamide, and 2, 4, 5, 6-tetra-oxohexahye-4-pyrimide or pyrimidine tetrone has been extensively used for in vivo induction of „chemical diabetesâ?? in animals. Administration of Pioglitazone reduced serum glucose level in alloxan (70 mg/kg) induced diabetic mice as compared to vehicle.

Индексировано в

Google Scholar
Открыть J-ворота
ResearchBible
CiteFactor
Космос ЕСЛИ
Индекс открытых академических журналов (OAJI)
научный руководитель
Publons
Импакт-фактор Международного инновационного журнала (IIJIF)
Международный институт организованных исследований (I2OR)
Cosmos
Женевский фонд медицинского образования и исследований
Секретные лаборатории поисковых систем
Евро Паб

Посмотреть больше