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Ferritin and its Biomedicine Application

Laurel Gregory, Chloe Santiago, Daisy Lindsey

Ferritin with Nano-caged structure is a widely existing protein in the biological world that regulates iron metabolism in organisms. It is characterized by uniform size, good biocompatibility, good pH/temperature stability, reversible self-assembly, and adjustable functionalization, which shows ideal potential for practical applications. In this reviews, we focus on the unique structure of ferritin, the relative position of the loaded cargo, and the important impact of this position on its applications, including biosynthesis, bioimaging, disease treatment, etc. Finally, the prospects of ferritin in biomedicine are also discussed.