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Effect of Betel leaf stalk Extract on Liver and Serum Profiles with Reference to Carbohydrate Metabolism in Male Albino Rats

Govardhan Naik A, Vengaiah V, Lalithamma A, Changamma C

The oral administration of Betel leaf stalk extract in male albino rats shows no influence on structural organization of liver. Reduction in liver proteins but elevation in serum proteins might be due to the mobilization towards blood. Reduction in liver and serum carbohydrates indicates hypoglycemia & some hepatic cell proliferation by administration. Due to the administration of leaf stalk extract more glucose is metabolized in to gluconate in liver leads to lowered serum glucose levels. There was no significant changes occur in liver glycogen over treatment represents anti-hyperglycemic activity of extract. Lactate which is an end product of the glycolytic pathway is an index of the relative aerobic or anaerobic nature of the tissue understudy. The enhanced pyruvic acid was due to higher glycolysis and more lactic acid was converted in to pyruvic acid.