Абстрактный

Bioinformatics Based Analysis of Microarrays in Human Bipolar Disorder

Rama Adiga , Rithika Adiga

Human brain disorder occurring in less than 30 age group termed bipolar disorder has no available cure or treatment. The diagnosis characterized by manic depression is based on psychopathology which makes it difficult to detect early. Development of biological markers is urgently required accompanied by new treatment approaches. The proteins expressed in the disease vs the normal conditions is a viable approach referred as microarray technology. An attempt has been made to analyse the microarray data using R statistics, to come up with knowledge of proteins expressed in bipolar disorder. The analysis provides probable biomarkers of the disease which could be developed as drug-targets.