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Antimicrobial Activity of Bacteriocin Produced by Staphylococcus aureus

Neha*, Bharti Mittu, Zarina Begum, Harjot Pal Kaur

Bacteriocin producing Staphylococcus aureus strain was isolated from skin swabs of healthy and infectious patients. Cell Free Supernatant (CFS) of culture was harvested for further investigation. It was then purified and analyzed for its affectivity against pathogenic microorganisms. The bacteriocin was produced by using a standard adsorption-desorption method and purified by high performance liquid chromatography. The antimicrobial activity of produced bacteriocin was detected against different strains. The produced bacteriocin is found to be significantly effective against food borne pathogens. The study concluded the possibility of using bacteriocin for food preservation as well as an extension of food life.